Sebaceous Carcinoma

Take a close look at this....Now go back and look at the chalazion. Always consider sebaceous cell carcinoma in the differential of recurring chalazion.

• General

  • Sebaceous carcinoma is more common than squamous cell carcinoma.
  • It is rare in patients under 40 years of age. More common in females and Asians

• Location

  • It occurs most commonly in the upper eyelid and is extremely rare elsewhere in the body. It can arise from meibomian glands, Zeis glands or sebaceous glands in caruncle.

• Differential Diagnosis

  • It may mimic Chalazion or chronic blepharoconjunctivitis.

• Factors associated with poor prognosis

  • Upper eyelid origin,
  • size greater than 10 millimeters
  • Meibomian gland origin
  • symptoms greater than 6 months
  • infiltrative growth pattern
  • pagetoid invasion
  • lymphatic or orbital invasion

• Treatment

  • Wide local excision with frozen section control

Sebaceous Cell Carcinoma involving the right upper, lateral and lower eyelid.